Alpha GPC stands for L-Alpha glycerylphosphorylcholine. It’s a naturally occurring cholinergic nootropic, but it can also be taken as a supplement. It’s best known for efficiently delivering choline to the brain. This helps create the neurotransmitter acetylcholine, which boosts cognition.
It’s believed to enhance many cognitive functions, help maintain essential neurochemical balance in the brain and promote cellular health.
Alpha GPC is naturally present in the body in trace amounts, and it’s also manufactured as a supplement using purified soy lecithin.
There are a few sources of Alpha GPC, such as organ meats, dairy products, and wheat germ. However, studies have shown that it only becomes pharmacologically active when it’s taken at high concentrations. This is only achieved through supplementation.
You can get Alpha GPC without a prescription as a dietary supplement in the US and Canada. It’s regulated in some European countries as a prescription drug used to treat Alzheimer’s.
Benefits and Effects
Alpha GPC is known for its positive physical and mental benefits. It can either be taken alone or stacked with other nootropics. The majority of the benefits are cognition-oriented, but it’s also been shown to improve muscular strength and physical health.
It protects brain health by encouraging the development of new brain cells. It helps the body repair damaged cell membranes. Some studies have shown Alpha GPC has a measurable neuroprotective effect. Others have suggested it may also have anti-aging benefits.
Increased Strength with Rapid Post-Workout Recovery
It stimulates the production of human growth hormone. There’s some research that shows it may improve the body’s capacity to build lean muscle mass and also to recover more quickly after a workout.
Improved Memory and Enhanced Cognition
Alpha GPC increases choline levels which improves cognition and facilitates the production of the neurotransmitter acetylcholine. This makes it effective in the treatment of memory loss and cognition deficits related to neurological disorders and age-related disorders, including stroke, Alzheimer’s disease, and vascular dementia.
How It Works
It’s a phosphatidylcholine, a lecithin phospholipid with a choline attachment. Choline is vital for the brain’s production of acetylcholine (“learning neurotransmitter”) that’s crucial for cognition.
As a water-soluble supplement, Alpha GPC is fast-acting and highly bioavailable when taken orally. It crosses the blood-brain barrier soon after it’s taken and users notice the effects within an hour. Every molecule of alpha GPC contains 40% choline, which is delivered directly to the brain.
The fact that it can cross the blood-brain border makes it a very efficient cholinergic at increasing circulating levels of choline in the central nervous system.
Studies have also shown it to increase levels of Serotonin and Dopamine. Which are neurotransmitters important in the regulation of energy, mood, and motivation. It also increases phosphatidylcholine levels, which promotes healthy cell structure, maintain the brain’s neurochemical balance and supports nerve signaling.
Phosphatidylcholine at low levels is associated with neurological disorders including Alzheimer’s disease, Schizophrenia, and dementia.
The recommended dosage is three doses of 400 mg. 1200 mg in total daily.
Alpha GPC is generally well-tolerated when taken at the recommended dose.
There have been occasional experiences of fatigue, nausea, headaches, gastrointestinal distress, nervousness, diarrhea, dizziness and low blood pressure in some individuals.
Most of the side effects have been reported when people have taken a high dose.
As it is a great source of choline and can be stacked with other nootropics, particularly the racetams.
Alpha GPC, Aniracetam, Noopept Stack
This stack is designed to provide an overall cognitive enhancement.
1–2x per day
Where to Buy
Have you used it before? What benefits did you experience?