Dimethylaminoethanol, or DMAE for short, is an natural chemical compound that’s produced in the brain naturally and can also be found in fish like salmon and sardines.
No wonder they call fish a brain food.
So, DMAE is an amino acid and there are several different jobs it has throughout the body.
When it comes to nootropics, it’s directly related to Choline, but because of a somewhat different chemical design it can cross into the brain much easier.
It’s also considered a precursor to the neurotransmitter acetylcholine which is responsible for all kinds of cognitive functions.
Basically acetylcholine boosts up your brain for things like memory and learning new things.
More on that subject later on.
The biggest reason why people seem to chose DMAE is because it has more of an obvious boost in cognitive functions.
There even a lot of people who take DMAE because of its natural powers in fighting off old age by promoting healthy skin, building up muscle tone and decreasing sagging.
But that’s for a whole other post later on down the road.
Anyway, let’s take a quick look at how DMAE does it’s thing in your brain.
How DMAE Works
Like I mentioned at the top, DMAE and Choline are very similar, but what makes them different is their basic designs.
The difference between the two is that DMAE only has 2 methyl molecules connected to its nitrogen molecule while Choline has 3 that are attached.
Let me explain just a little bit here.
Because DMAE only has 2 methyl molecules it can get across the blood-brain barrier a lot easier than many other Choline supplements.
So, as soon as DMAE makes its way into brain cells, it’s transformed into Acetylcholine.
This is where the good stuff starts to happen.
Acetylcholine is a chemical that is a highly effective neurotransmitter which has an essential part in many mental functions like forming memory, focus, and learning new things.
It is recognized as probably the most essential neurotransmitters for any development of new connections among neurons as well as plasticity in the brain.
Researchers believe that as much as 90% of the population are viewed as lacking when it comes to the nutritional requirements necessary to make acetylcholine.
It is also thought that this amount could be even higher in elderly people.
So, are you getting enough of the right stuff to make Acetylcholine naturally?
Anyway, let’s keep moving…
Using acetylcholine supplements are frequently needed to make sure you have the best brain functions you possibly can.
DMAE is among the best options out there for boosting levels of the neurotransmitter Acetylcholine.
Centrophenoxine, which happens to be created from DMAE, is known to be much more potent and is used in repairing brain damage for some stroke patients.
DMAE can join to phospholipids inside brain and because of this ability it helps a lot of the supplement get included into the neural walls that exist in the brain.
What does that do for you exactly?
This action is thought to be in charge of acting like antioxidant in addition to helping boost brain and neural health.
DMAE also helps to boost the fluidity and absorbing power of the nerve membranes, so that they can get all the essential nutrition taken in and get rid of waste.
Cell membrane fluidity is slowed down as we get older, but DMAE might be able to change or stop these signs of maturing from happening.
Now that you have an idea of how it works we can jump into the benefits.
The research on DMAE shows that it can boost neural functions along with positive effects on intelligence.
This is likely because of the fact that DMAE speeds up the fusion of acetylcholine inside the brain.
As I already mentioned, Acetylcholine is a neurotransmitter that neurons use to communicate when making and recalling memories as well as a bunch of other neural processes.
Increased amounts of acetylcholine can cause better clarity of thought, memory retention, focus, and analytical skills.
Anyway, let’s get on to the specific benefits of DMAE
The most typical user of DMAE says that they feel improved memory, concentration and mental functionality.
Research done by Duke University in 1995 found that when rats were given DMAE proved upgrades in working memory effectiveness.
Even though it hasn’t been clinically proven, there are plenty of reports that taking DMAE can treat some symptoms of depression. A 2003 study had an optimistic result for people identified as having “emotional borderline disturbance”.
DMAE is additionally believed to help lessen levels of anxiety, give an energy boost, and increase vitality.
A fairly unique benefit of DMAE is that it will generate lucid a dreaming state while you sleep.
In a lucid dreaming state, you know that you’re really dreaming but you’re able to control what’s going on in the dream.
Lucid dreaming is known to improve creativity and problem solving, as well as help in boosting mood.
Some people tend to think it’s useful for athletic training or any other task that needs extreme concentration and focus.
Several studies from the 1970’s have shown that those with ADD/ADHD have found that DMAE has been able to increase focus and lower impulse control issues.
Dosage for DMAE
Simply because everyone have a different body chemistry there is a wide range of doses that can be taken with DMAE.
DMAE is generally dosed between 25 mg and going all the way up to 750 mg and are taken twice a day.
It’s a good idea to assess the effects and figure out what is going to be the best dosage for your body chemistry.
It’s a Nootropic that you are going to get more “bang for your buck” when you use less.
What I am trying to say is usually using smaller dosages are going to the effects you are looking for as opposed to taking huge amounts.
When you decide to get started using DMAE it is a good idea to start of with a dose of less the 100 mg for the first week or so.
By doing this you are going to give your body a shot getting adjusted to it and you’ll be able to get a good idea of the effects it has.
So, how much should you take once you get adjusted?
A lot of people end up using a dose of around 100 to 300 mg a day after their body has adjusted to DMAE.
So, that would be 50 to 150 mg twice a day.
Like many Nootropics, it is important to know that you should not rush into it.
Take time to make sure you find the right dosage for you.
Also, I got to tell you that there have been reports where people who take 1200 mg a day or more can end up with depression like symptoms.
But, after lowering the dosage down to around 50 mg these symptoms will lessen and should be gone in a few days.
If you stack DMAE with other Nootropics there is most likely going to be a solid boost in each of the ingredients effects.
So, even if you have been using DMAE for a while you might want to bring down the dosage at least at in the beginning of using it in a stack.
Before you rush out and start using DMAE we have to talk about side effects first.
Safety and Side Effects for DMAE
It’s time to go over some important info about DMAE, so make sure you are paying attention.
Ok, first off when you take DMAE at the recommended doses side effects are not common.
But this does not mean they can’t or won’t happen.
So, with that being said, some of possible side effects are:
- gastrointestinal problems
- body odor
- increased blood pressure
Overdosing with DMAE is considered difficult because of the low toxicity and wide range of safe dosage.
You should also know that people who are prone to depression, schizophrenic, pregnant,or lactating should not use DMAE.
Your best bet is to talk with a doctor before using this or any supplement no matter how good your health is.
Ok now all that stuff is out of the way, let’s about where to get DMAE.
You can get DMAE at a lot of health food stores, GNC, or even amazon, but many DMAE supplements are market for antiaging and not for cognitive function.
I guess that really doesn’t matter, but if you are going to spend your hard earned cash why not really get something out of it?
But, I would really suggest buying one of the more researched nootropics like Centrophenoxine.
I say this because the effects are similar, but it is much more potent and effective.
Check out PeakNootropics.com if you decide to pick some up or are looking for the best nootroopics online.
Ok, what’s next?
Let’s talk about stacking DMAE!
The DMEA and Piracetam Stack
The concept driving the Piracetam and DMAE stack would be that the choline in DMAE can result in increased amounts of acetylcholine to ensure that Piracetam’s effects are even stronger.
Just like when cranking up the grill you need charcoal, the fuel, and lighter fluid, the propellant to get it burning quickly. Without the fuel, like charcoal, to keep it going the fire simply won’t last.
Basically, when you combine them, you’re supplying Piracetam more fuel to keep it going.
Since there are some legit doubts about how useful DMAE is, most neuroscience studies have concentrated much more on the results of Centrophenoxine which is actually a DMAE offshoot that has a lot more potency.
Tons of studies and user feedback validate the strength of Centrophenoxine, specially when it’s put together with Piracetam.
If you decide to use a DMAE and Piracetam stack and aren’t satisfied with the results, you might want to step up to a Centrophenoxine and Piracetam stack.
When dosing the Piracetam and DMAE stack using a10:1 dosage portion ratio is recommended.
So, with 2000 mg of Piracetam you’d want to add 200 mg of DMAE. Some people go so far as to use a 20 to 1 ratio because they feel it works better.
Now, there’s much less proof that supports DMAE over other nootropics, but many people rely on its capability to boost focus and mood.
Basically the results are going to differ for every person.
Some common alternatives to a DMAE and Piracetam stack, could be using supplements like CDP Choline, Alpha GPC or Hydergine.
Ahead of building your very own stack, take a look at each of the options to see what might work best for you.
Overall DMAE is a safe nootropic supplement because of its minimal side effects, low toxicity and wide range of safe doses.
DMAE benefits are pretty solid, but depending on individual body chemistry the effects can very.
If you happen to give DMAE a shot and it doesn’t do what you need it to do, there are plenty of alternatives out there that have plenty of solid reviews and research behind them.
Centrophenoxine is probably the best option as an alternative, but Alpha GPC and CDP Choline are the most well known and liked.
Just remember to start slow and work your way up to get the most out of DMAE.